Inflammatory demyelinating polyneuropathies in children

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Acquired Inflammatory Demyelinating Polyneuropathies: Clinical and Electrodiagnostic

The acquired demyelinating polyneuropathies include acute (AIDP, Guillain-Barre syndrome, GBS) and chronic (CIDP, dysproteinemic) forms which differ primarily in their temporal profile. They are inflammatory-demyelinating diseases of the peripheral nervous System and likely have an immunologic pathogenesis. Although these neuropathies usually have a characteristic presentation, the electromyogr...

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Decreased electrical excitability of peripheral nerves in demyelinating polyneuropathies.

Not recognising the presence of decreased excitability may give rise to a seemingly low compound muscle action potential, which may lead erroneously to the conclusion of conduction block. To quantify decreased electrical excitability, stimulation-response curves and the current needed to achieve 90% of the maximal compound muscle action potential amplitude, i90, were obtained in 17 healthy cont...

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Current treatments of chronic immune-mediated demyelinating polyneuropathies.

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), multifocal motor neuropathy (MMN), and anti-myelin-associated glycoprotein (anti-MAG) neuropathy are three demyelinating acquired neuropathies, with distinct responses to immunotherapy. In placebo-controlled, double-blind, randomized trials, intravenous immunoglobulin (IVIg) has been effective for CIDP and MMN, and plasmapheresis...

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Child neurology: chronic inflammatory demyelinating polyradiculoneuropathy in children.

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune disorder characterized by patchy demyelination of nerve roots and distal nerves. The course may be monophasic progressive or relapsing-remitting. CIDP is less common in children than in adults. As in adults, children with CIDP present with proximal and distal weakness and loss of deep tendon reflexes. Children are...

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Chronic inflammatory demyelinating polyneuropathy.

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is a rare neurological disease. Definitive therapy is not yet established. We report our use of intravenous Immunoglobulin (iv IgG) in two cases of CIDP and review the therapeutic options available. Intravenous IgG is a ubiquitous practical treatment particularly in patients who do not respond to steroids and where a rapid response is req...

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ژورنال

عنوان ژورنال: Russian Pediatric Journal

سال: 2019

ISSN: 2413-2918,1560-9561

DOI: 10.18821/1560-9561-2016-19-3-183-191